Magnesium alloy for biodegradable and antibacterial orthopaedic implants—Sheep model preclinical trial.
The project will test the biocompatibility of the novel alloy and assess local tissue reaction and fracture healing at the test site as well as systemic absorption of metabolites.
Project status
Content navigation
About
We have organized this research activity to test our materials using sheep model. Dr Alexandra Bobinskas, our PhD student, and a senior staff specialist of oral and facial surgery at TCH has arranged a large animal test using sheep model on the 3B (Biocompatible, Bioactive and Biodegradable) material developed in our laboratory. This is in collaboration with Charles Sturt Veterinary Services. The project will test the biocompatibility of the novel alloy and assess local tissue reaction and fracture healing at the test site as well as systemic absorption of metabolites. If successful, we aim to undertake an expanded this study, more closely analogous to human surgical applications in 2024 before submission an application on human clinical trial to TGA (Therapeutic and Drug Administration, Australia) and to FDA (Food and Drug administration, USA).
Members
Principal investigator
Co-investigator
Other members
- Professor Xiaobo Chen