Magnesium alloy for biodegradable and antibacterial orthopaedic implants—Sheep model preclinical trial.

The project will test the biocompatibility of the novel alloy and assess local tissue reaction and fracture healing at the test site as well as systemic absorption of metabolites.

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This project is open for Honours, Masters, MPhil and PhD students.
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Project status

Current

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About

We have organized this research activity to test our materials using sheep model. Dr Alexandra Bobinskas, our PhD student, and a senior staff specialist of oral and facial surgery at TCH has arranged a large animal test using sheep model on the 3B (Biocompatible, Bioactive and Biodegradable) material developed in our laboratory. This is in collaboration with Charles Sturt Veterinary Services. The project will test the biocompatibility of the novel alloy and assess local tissue reaction and fracture healing at the test site as well as systemic absorption of metabolites. If successful, we aim to undertake an expanded this study, more closely analogous to human surgical applications in 2024 before submission an application on human clinical trial to TGA (Therapeutic and Drug Administration, Australia) and to FDA (Food and Drug administration, USA).

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Biocompatibility

Members

Principal investigator

Rachel Li

Associate Professor, Trauma and Orthopaedic Research Unit

Co-investigator

No photo provided

Honorary Senior Lecturer
PhD Scholar, School of Medicine and Psychology
Oral and Maxillofacial Surgeon, Canberra Health Services

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Orthopaedic Surgeon Orthopaedics ACT
Honorary Professor, ANU School of Medicine and Psychology
Leader, Research Unit of Trauma and Orthopaedic Surgery